pain-response is similar to fight or flight.
natural=occurs freely in nature. Point to any other part of nature that meets anything that you're saying (builds civilizations and large-scale communities, domesticates other animals, modifies other organisms genetically, etc etc etc) and you have an argument. Until then, you're stuck citing the EXCEPTION (humans) as your evidence, but that's a logical fallacy. My repetition exists solely for the purpose of your cognitive registration.
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