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Vulgar no story, true fact...things dont always behave the same way once taking out of a controlled environment; moreover time is a factor...and the length of that time is one of many variables.
In the most simplest example i can give, although the result is very different, think of the progression of cancer, first it affects the cell, the cell then undergoes a mutation and becomes immortalized, once immmortilized it continues to replicate producing more mutated cells till all those cells ultimately affect the cellular functions, once cellular function is disrupted the sorrounding tissue is then altered, these changes in the tissue are then passed onto the organ that the tissue comprises, once the organ is altered the cycle then perpetuates itself, dividing and replicating untill ultimatley the entire system has been affected...this is metasis...one cell, one alteration, that causes it to become immortallized, while continuing to replicate till it over runs the entire system. Cell, function, tissue, organ, system...this is why tumors grow at alarming rates. now imagine the same kind of process with a totally unknown and unpredicatble mutation ultimately resulting in idiopathic system alterations and mutations...each one differing bc each mutation can occur at an unknown loci, and these loci contribute to its function ...with absolutely no immunity to slow the rate of mutation and no medicine or treatment to counteract the affects bc the cause remains unknown.